Breast Cancer Resistance Protein Inhibitors [MoA] class drugs

65 results

  • akynzeo - netupitant and palonosetron capsule

    (Netupitant And Palonosetron)
    Helsinn Therapeutics (U.S.), Inc.
    AKYNZEO (palonosetron/netupitant) is used with dexamethasone in adults to prevent acute and delayed nausea and vomiting from cancer chemotherapy, including highly emetogenic regimens. Available as capsules for broad chemotherapy use and as an injection for highly emetogenic chemotherapy only.
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  • alyftrek - vanzacaftor, tezacaftor, and deutivacaftor tablet, film coated

    (Vanzacaftor, Tezacaftor, And Deutivacaftor)
    Vertex Pharmaceuticals Incorporated
    Alyftrek treats cystic fibrosis (CF) in adults and children 6 years and older with at least one CFTR gene variant responsive to treatment or that produces CFTR protein.
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  • ayvakit - avapritinib tablet, film coated

    (Avapritinib)
    Blueprint Medicines Corporation
    Ayvakit treats adults with unresectable or metastatic GIST harboring PDGFRA exon 18 mutations (including D842V), advanced systemic mastocytosis (ASM, SM-AHN, mast cell leukemia), and indolent systemic mastocytosis. Not recommended when platelet counts are below 50 × 10⁹/L.
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  • epclusa - velpatasvir and sofosbuvir tablet, film coated

    (Velpatasvir And Sofosbuvir)
    Gilead Sciences, Inc.
    Epclusa treats chronic hepatitis C virus (HCV) genotypes 1–6 in adults and children aged 3 and older. It is used with or without cirrhosis; patients with decompensated cirrhosis take it in combination with ribavirin.
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  • evotaz - atazanavir and cobicistat tablet

    (Atazanavir And Cobicistat)
    E.R. Squibb & Sons, L.L.C.
    EVOTAZ combines atazanavir (HIV-1 protease inhibitor) and cobicistat (CYP3A inhibitor) for treating HIV-1 infection in adults and pediatric patients weighing at least 35 kg, used alongside other antiretroviral agents. Treatment-experienced patients should be guided by baseline protease inhibitor resistance substitutions.
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  • filspari - sparsentan tablet, film coated

    (Sparsentan)
    Travere Therapeutics, Inc.
    Filspari slows kidney function decline in adults with primary immunoglobulin A nephropathy (IgAN) who are at risk for disease progression.
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  • genvoya - elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide tablet

    (Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide)
    Gilead Sciences, Inc.
    Genvoya is a complete HIV-1 treatment regimen for adults and children weighing at least 25 kg, used in treatment-naive patients or to replace current therapy in those virologically suppressed on stable antiretrovirals for at least 6 months with no treatment failure or resistance history.
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  • harvoni - ledipasvir and sofosbuvir tablet, film coated

    (Ledipasvir And Sofosbuvir)
    Gilead Sciences, Inc
    Harvoni treats chronic hepatitis C virus (HCV) in adults and pediatric patients aged 3 and older with genotype 1, 4, 5, or 6 infection, with or without cirrhosis. Used with ribavirin for decompensated cirrhosis or liver transplant recipients with genotype 1 or 4 infection.
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