Medications for Aggressive Systemic Mastocytosis

2 results
  • ayvakit - avapritinib tablet, film coated

    (Avapritinib)
    Blueprint Medicines Corporation
    Ayvakit treats adults with unresectable or metastatic GIST harboring PDGFRA exon 18 mutations (including D842V), advanced systemic mastocytosis (ASM, SM-AHN, mast cell leukemia), and indolent systemic mastocytosis. Not recommended when platelet counts are below 50 × 10⁹/L.
  • rydapt - rydapt capsule, liquid filled

    (Rydapt)
    Novartis Pharmaceuticals Corporation
    RYDAPT treats adults with newly diagnosed FLT3 mutation-positive AML in combination with chemotherapy (not as single-agent induction), and adults with aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematological neoplasm (SM-AHN), or mast cell leukemia (MCL).