Organic Anion Transporting Polypeptide 1B3 Inhibitors [MoA] class drugs

18 results
  • epclusa - velpatasvir and sofosbuvir tablet, film coated

    (Velpatasvir And Sofosbuvir)
    Gilead Sciences, Inc.
    Epclusa treats chronic hepatitis C virus (HCV) genotypes 1–6 in adults and children aged 3 and older. It is used with or without cirrhosis; patients with decompensated cirrhosis take it in combination with ribavirin.
  • evotaz - atazanavir and cobicistat tablet

    (Atazanavir And Cobicistat)
    E.R. Squibb & Sons, L.L.C.
    EVOTAZ combines atazanavir (HIV-1 protease inhibitor) and cobicistat (CYP3A inhibitor) for treating HIV-1 infection in adults and pediatric patients weighing at least 35 kg, used alongside other antiretroviral agents. Treatment-experienced patients should be guided by baseline protease inhibitor resistance substitutions.
  • genvoya - elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide tablet

    (Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide)
    Gilead Sciences, Inc.
    Genvoya is a complete HIV-1 treatment regimen for adults and children weighing at least 25 kg, used in treatment-naive patients or to replace current therapy in those virologically suppressed on stable antiretrovirals for at least 6 months with no treatment failure or resistance history.
  • lupkynis - voclosporin capsule

    (Voclosporin)
    Aurinia Pharma U.S., Inc.
    Lupkynis is indicated, alongside background immunosuppressive therapy, for the treatment of active lupus nephritis in adults. Not recommended in combination with cyclophosphamide.
  • mavyret - glecaprevir and pibrentasvir tablet, film coated

    (Glecaprevir And Pibrentasvir)
    Abbvie Inc.
    Mavyret treats acute or chronic hepatitis C (genotypes 1–6) in adults and children 3+ without cirrhosis or with compensated cirrhosis. Also indicated for genotype 1 patients previously treated with an NS5A inhibitor or NS3/4A protease inhibitor (but not both).
  • prevymis - letermovir tablet, film coated

    (Letermovir)
    Merck Sharp & Dohme Llc
    Prevymis prevents cytomegalovirus (CMV) infection and disease in CMV-seropositive adults and children (6 months+, ≥6 kg) receiving an allogeneic stem cell transplant, and in adults and adolescents (12 years+, ≥40 kg) who are high-risk kidney transplant recipients (CMV-positive donor, CMV-negative recipient).
  • prezcobix - darunavir ethanolate and cobicistat tablet, film coated

    (Darunavir Ethanolate And Cobicistat)
    Janssen Products, Lp
    Prezcobix and Prezcobix Ped are used with other antiretrovirals to treat HIV-1 in treatment-naïve and treatment-experienced adults and pediatric patients 3 years and older weighing at least 15 kg with no darunavir resistance-associated substitutions.
  • rezdiffra - resmetirom tablet, coated

    (Resmetirom)
    Madrigal Pharmaceuticals, Inc.
    REZDIFFRA is used with diet and exercise to treat adults with noncirrhotic NASH and moderate-to-advanced liver fibrosis (stages F2–F3). Approved under accelerated approval. Not for use in patients with decompensated cirrhosis.