Multidrug and Toxin Extrusion Transporter 1 Inhibitors [MoA] class drugs

14 results

  • ayvakit - avapritinib tablet, film coated

    (Avapritinib)
    Blueprint Medicines Corporation
    Ayvakit treats adults with unresectable or metastatic GIST harboring PDGFRA exon 18 mutations (including D842V), advanced systemic mastocytosis (ASM, SM-AHN, mast cell leukemia), and indolent systemic mastocytosis. Not recommended when platelet counts are below 50 × 10⁹/L.
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  • evotaz - atazanavir and cobicistat tablet

    (Atazanavir And Cobicistat)
    E.R. Squibb & Sons, L.L.C.
    EVOTAZ combines atazanavir (HIV-1 protease inhibitor) and cobicistat (CYP3A inhibitor) for treating HIV-1 infection in adults and pediatric patients weighing at least 35 kg, used alongside other antiretroviral agents. Treatment-experienced patients should be guided by baseline protease inhibitor resistance substitutions.
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  • genvoya - elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide tablet

    (Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide)
    Gilead Sciences, Inc.
    Genvoya is a complete HIV-1 treatment regimen for adults and children weighing at least 25 kg, used in treatment-naive patients or to replace current therapy in those virologically suppressed on stable antiretrovirals for at least 6 months with no treatment failure or resistance history.
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  • pemazyre - pemigatinib tablet

    (Pemigatinib)
    Incyte Corporation
    Pemazyre treats adults with previously treated, unresectable locally advanced or metastatic cholangiocarcinoma with an FGFR2 fusion or rearrangement, and adults with relapsed or refractory myeloid/lymphoid neoplasms with FGFR1 rearrangement.
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  • prezcobix - darunavir ethanolate and cobicistat tablet, film coated

    (Darunavir Ethanolate And Cobicistat)
    Janssen Products, Lp
    Prezcobix and Prezcobix Ped are used with other antiretrovirals to treat HIV-1 in treatment-naïve and treatment-experienced adults and pediatric patients 3 years and older weighing at least 15 kg with no darunavir resistance-associated substitutions.
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  • recorlev - levoketoconazole tablet

    (Levoketoconazole)
    Xeris Pharmaceuticals, Inc.
    Recorlev treats endogenous hypercortisolemia in adults with Cushing's syndrome when surgery is not an option or has not been curative. Not approved for fungal infections.
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