Kinase Inhibitor [EPC] class drugs

104 results

  • afinitor - everolimus tablet

    (Everolimus)
    Novartis Pharmaceuticals Corporation
    Afinitor treats advanced HR+/HER2- breast cancer (with exemestane), progressive neuroendocrine tumors (pancreatic, GI, or lung), advanced renal cell carcinoma, and tuberous sclerosis complex (TSC)-associated renal angiomyolipoma, SEGA, and partial-onset seizures in adults and pediatric patients.
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  • alunbrig - brigatinib tablet, film coated

    (Brigatinib)
    Takeda Pharmaceuticals America, Inc.
    Alunbrig treats adult patients with ALK-positive metastatic non-small cell lung cancer (NSCLC) as detected by an FDA-approved test.
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  • augtyro - repotrectinib capsule

    (Repotrectinib)
    E.R. Squibb & Sons, L.L.C.
    Augtyro treats adults with locally advanced or metastatic ROS1-positive non-small cell lung cancer. It also treats adults and patients aged 12+ with locally advanced or metastatic NTRK gene fusion-positive solid tumors that have progressed on prior treatment or have no satisfactory alternative therapy.
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  • ayvakit - avapritinib tablet, film coated

    (Avapritinib)
    Blueprint Medicines Corporation
    Ayvakit treats adults with unresectable or metastatic GIST harboring PDGFRA exon 18 mutations (including D842V), advanced systemic mastocytosis (ASM, SM-AHN, mast cell leukemia), and indolent systemic mastocytosis. Not recommended when platelet counts are below 50 × 10⁹/L.
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  • balversa - erdafitinib tablet, film coated

    (Erdafitinib)
    Janssen Products Lp
    BALVERSA treats adults with locally advanced or metastatic urothelial carcinoma with susceptible FGFR3 genetic alterations whose disease progressed after at least one prior systemic therapy. Patient selection requires an FDA-approved companion diagnostic. Not recommended for patients eligible for PD-1/PD-L1 inhibitor therapy who have not yet received it.
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  • brukinsa - zanubrutinib capsule

    (Zanubrutinib)
    Beone Medicines Usa, Inc.
    BRUKINSA is a kinase inhibitor for adults with mantle cell lymphoma, Waldenström's macroglobulinemia, chronic lymphocytic leukemia or small lymphocytic lymphoma, relapsed/refractory marginal zone lymphoma, and relapsed/refractory follicular lymphoma (with obinutuzumab).
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  • calquence - acalabrutinib tablet, film coated

    (Acalabrutinib)
    Astrazeneca Pharmaceuticals Lp
    CALQUENCE treats adults with mantle cell lymphoma (MCL) — either previously untreated (with bendamustine and rituximab, when ineligible for stem cell transplant) or after prior therapy — and adults with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).
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  • caprelsa - vandetanib tablet, film coated

    (Vandetanib)
    Genzyme Corporation
    Caprelsa treats symptomatic or progressive medullary thyroid cancer in adults with unresectable locally advanced or metastatic disease. Use with caution in patients with indolent, asymptomatic, or slowly progressing disease due to treatment-related risks.
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